UofL BE Seminar Series: Landon Teer, PhD Candidate: The Biophysical Regulation of GBM Invasion and Immunosuppression
GBM is a highly aggressive form of brain cancer with a dismal prognosis resulting from high rates of tumor cell adaptation and immune evasion. In recent years, biophysical stimuli of the tumor microenvironment (TME) have been identified as critical regulators of these protumorigenic changes. Immunotherapies have thus far been limited in preventing these changes and improving patient outcome in solid tumor cancers such as GBM, in part, due to a lack of understanding of the interactions between the biophysical regulators and the immune cells of the TME. Further studies to unravel these complex interactions can be leveraged in engineering systems to bolster therapy efficacy and improve patient outcome.
Friday, February 16 at 12:00pm to 1:00pm
Belknap Academic Building, 125
201 E. Shipp Street Walk, Louisville, KY 40208